Word: retinitis
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...Retin-A right now and I do think that works. The other creams might actually reduce your wrinkles the tiniest bit because some of them make claims that they do. The problem is, nobody is examining your face as closely as you do. What I learned after a year - this is really to me the take-home message - is that there's good news and bad news. The bad news is that it's very difficult, if not impossible, to look younger. But the good news is that it's possible and actually relatively easy and inexpensive to appear more...
First across the finish line, in 1995, was Ortho Dermatological's prescription cream Renova, a less concentrated form of its antiacne medication Retin-A. The two are the only products that have been medically proved to reduce fine lines. Their active ingredient, a form of vitamin A called tretinoin, does at least two things: it boosts the development of firm new keratinocytes and smooths tiny creases in the upper layers of the epidermis. The downside: some women find it irritates their skin too much...
...already been proved. Says Dr. Martin Raber, physician in chief of the M.D. Anderson Cancer Center in Houston: "It is accepted practice that once a drug is FDA-approved it can be freely used." But the FDA gets nervous when a drug's unapproved uses overshadow its original purpose. Retin-A cream, for example, was approved by the FDA for the treatment of acne in 1971, but then, much to the FDA's consternation, it was widely prescribed to smooth wrinkles caused by aging and overexposure...
...Johnson & Johnson subsidiary says it will plead guilty tomorrow to obstructing a federal probe of how it marketed Retin-A, an acne drug commonly prescribed as a wrinkle remover. The firm, Ortho Pharmaceuticals of Raritan, N.J., agreed to pay $7.5 million in fines and dismiss three senior employees who shredded documents sought by investigators. The U.S. Food and Drug Administration launched its investigation in 1991, concerned that Ortho had been promoting Retin-A for a non-approved use as a wrinkle cream...
...antiwrinkle cream Retin-A may have an important side effect: it reverses a condition that sometimes leads to cervical cancer, and it can erase the moles that are precursors of the lethal skin cancer melanoma...