Word: rhesus
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Dates: during 1980-1989
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...estimated 70% to 80% of heroin addicts. Methadone also tends to reduce coke use, but less dramatically. While methadone may wean half of those treated from cocaine, buprenorphine could slash the number of coke abusers to almost nil, says Yale researcher Thomas Kosten. A Harvard study of rhesus monkeys habituated to using coke found that daily doses of buprenorphine led the monkeys to kick the habit completely...
...sure the scientists at the flight center in Moscow have rigged up a model containing another rhesus monkey with a free left arm -- all to see what mischief I'm capable of. They needn't worry. I will do nothing to embarrass the motherland. Besides, I can't leave my seat. I cannot reach any levers. Nor can I leave my chamber to visit the fish and the mice on board for experiments. What this biosatellite needs is some of your perestroika -- you know, restructuring. Space flight might then be more fun than a barrel of monkeys. Sincerely yours, Yerosha
...into the brain and damaged the same area affected by Parkinson's disease. No other substance is known to do that. Last April Dr. Irwin Kopin of the National Institute of Mental Health, co-author of the journal article, announced that he had used MPTP to induce Parkinsonism in rhesus monkeys. The work of these two men suggests that the previously unexplained symptoms of Parkinson's might result from exposure to MPTP, and thus that the disease itself may be caused by environmental factors...
Upjohn has been haunted, however, by its own early tests of Depo-Provera in animals. In a seven-year, controlled study using beagles, two out of 16 dogs developed breast cancer. Results from a ten-year study using 52 rhesus monkeys were equally alarming: two of the animals developed cancer of the endometrium (the lining of the uterus). Upjohn's own scientists concluded in 1978 that the cancer was "likely related to treatment with Depo-Provera." Later that year the FDA refused to allow Upjohn to market the drug as a contraceptive, though it is approved for treating certain...
Since then, Upjohn has challenged the validity of its own tests. According to company scientists and a number of outside experts, both beagles and rhesus monkeys are highly sensitive to progesterone and are more likely than humans to develop cancer in response to it. Depo-Provera partisans further claim that there has been no increase in the rate of cancer among women taking the drug in countries where it is approved. Says Gynecologist Elizabeth Connell of Atlanta's Emory University: "It appears to be as safe or perhaps safer than oral contraceptives or intrauterine devices...