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Upjohn has been haunted, however, by its own early tests of Depo-Provera in animals. In a seven-year, controlled study using beagles, two out of 16 dogs developed breast cancer. Results from a ten-year study using 52 rhesus monkeys were equally alarming: two of the animals developed cancer of the endometrium (the lining of the uterus). Upjohn's own scientists concluded in 1978 that the cancer was "likely related to treatment with Depo-Provera." Later that year the FDA refused to allow Upjohn to market the drug as a contraceptive, though it is approved for treating certain...

Author: /time Magazine | Title: Medicine: Effective, but How Safe? | 1/24/1983 | See Source »

Launching a group of rhesus monkeys with the shuttle's Spacelab in 1984, Moore-ede believes he will confirm his finding that a shift of blood in the monkeys from the lower extremities to the torso because of changes in gravity accelerates their loss of fluids and purges high levels of potassium...

Author: By James L. Tyson, | Title: Harvard Project in Shuttle's Spacelab Aims to Smooth Adaptations to Space | 4/8/1981 | See Source »

Both creatures appear to have weighed roughly 30 Ibs. and somewhat resembled a rhesus monkey in body form and size. Their diet was probably fruits and other vegetation. As Savage says: "They were a sort of monkey with apelike teeth, bouncing through the trees." They could thus emerge as an earlier common ancestor than Aegyptopithecus of both apes and monkeys, and as a link back to such lower primates as lemurs and tarsiers. That might put them very near the start of anthropoid evolution; Ciochon speculates that they may have migrated into Africa via western Asia to evolve into later...

Author: /time Magazine | Title: Science: Asian Roots? | 5/21/1979 | See Source »

...loss of sexual drive, and spontaneous abortions in laboratory. While scientists agree that the evidence is not yet conclusive, one study seems to bear out claims that dioxin is harmful to human beings. A scientist at the University of Wisconsin, Dr. James Allen, conducted a series of tests on rhesus monkeys, the animal most like humans in chemical sensitivity. He found that dioxin administered over a period of months in dosages as low as 550 parts per trillion, caused cancer and eventual death. Allen fed dioxin to monkeys in amounts comparable to those consumed by people eating contaminated fish, vegetables...

Author: By Susan D. Chira, | Title: Chemical Warfare at Home and Abroad | 9/20/1978 | See Source »

...Bound Brook, NJ. A flamboyant showman, Trefflich built a million-dollar-a-year business selling exotic creatures from his four-story Lower Manhattan menagerie to scientists, moviemakers and carnival hucksters. Among his sales: Tarzan's chimp Cheetah and the monkeys used in breakthrough Rh (rhesus) factor research. Occasionally a restless snake would escape from Trerflich's store; once 100 monkeys created harmless havoc on Wall Street and made the headlines. Trefflich claimed the escape was accidental; skeptics abounded...

Author: /time Magazine | Title: Milestones, Jul. 24, 1978 | 7/24/1978 | See Source »

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