Word: rheumatoid
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Dates: during 1950-1959
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Doctors have long noted that pregnancy relieves women suffering from rheumatoid arthritis. Blood serum taken from new mothers soon after delivery has even proved effective in treating the disease (TIME, Nov. 27). Rather than take blood from new mothers, Dr. Tufts decided to try something else. The same factor that prevents arthritis in pregnant women and infants (who never have arthritis), he reasoned, must lie in the blood of the placenta, gallons of which are thrown away every day in any obstetrical center...
Doctors noted long ago that women get relief from rheumatoid arthritis during pregnancy, then relapse within a couple months. Why does pregnancy have this effect? Some arthritis researchers have tried to find a drug or chemical which would get the same results (hence, ACTH and cortisone treatments). Dr. Louis W. Granirer of Queens General Hospital in New York City reasoned that the healing substance was probably in the blood of pregnant women, and probably stayed there for a while after childbirth...
...substances found in the adrenal glands to 28, and Kendall kept trying to synthesize compound E, or something like it. At last Kendall and others succeeded, and late in 1948, a colleague at the Mayo Clinic, Dr. Philip Hench, directed the first injections of cortisone to human victims of rheumatoid arthritis. The results were dramatic. Suddenly, a vast new field of medical research was opened...
...stage of exhaustion. This was what Dr. Selye had found in his rats in 1936, shown by enlarged and overactive adrenals, wasted thymus and bleeding ulcers. But exhaustion, the last phase, may produce many other "diseases of adaptation," notably some types of high blood pressure, several kidney diseases, rheumatoid and gouty arthritis...
...Finger Exercises." Long before Hench and Kendall showed the near-miraculous power of ACTH and cortisone to reverse the course of rheumatoid arthritis (TIME, May 2, 1949), Dr. Selye had outlined the theory into which their facts fitted so neatly. He has become the world's outstanding expert on the endocrine glands-though many dispute some aspects of his theories and some question his methods...