Word: rheumatoid
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Dates: during 1970-1979
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...past few years, usually in summer or fall, dozens of people in eastern Connecticut-both children and adults-have been stricken with these painful and puzzling symptoms, which often come in repeated episodes that last for weeks and even months at a stretch. At first, doctors suspected rheumatoid arthritis, a serious disease of still unknown origin that can permanently cripple the joints. Then, learning that almost all the victims lived in three adjoining towns along the Connecticut River-Lyme, Old Lyme and East Haddam (total population 12,000)-medical investigators from the Yale University School of Medicine came...
...complex will provide obstetrical, gynecological, surgical and medical care, and serve patients with arthritis and rheumatoid conditions...
...addition to these dramatic results, doctors now know more than ever before about what happens in such autoimmune diseases as rheumatoid arthritis and systemic lupus erythematosus, in which the immune system goes haywire, recognizes certain of the body's own tissues as foreign, and destroys them. They can also treat these illnesses with drugs that suppress the immune system, relieving the symptoms at the risk of leaving the body open to infection. But they have yet to learn the exact causes, let alone the cures for these diseases, which affect more than 5.5 million Americans...
...released after the operation, the testicles continue to produce them. Reabsorbed by the body, the sperm products sometimes cause an immune response that in turn may destroy or immobilize newly produced sperm cells. This could conceivably increase a man's susceptibility to disorders related to autoimmune reactions like rheumatoid arthritis. While there is no proof as yet of his theory, which is based on unsubstantiated reports of ten cases, researchers agree that further investigation is essential...
...Among the causes of pain in rheumatoid arthritis are inflammation of the synovium (the membrane lining the joint capsule) and subsequent erosion of the enclosed cartilage and bone. Doctors generally prescribe painkillers and other anti-inflammatory drugs including common aspirin. But according to Dr. Alan Wilde of the Cleveland Clinic, early surgery may provide more permanent relief and slow the progress of the disease as well. Wilde told a scientific session of the Arthritis foundation that he had performed synovectomies on 39 patients, delicately removing the inflamed tissue from a total of 121 finger joints. Most of the patients experienced...