Word: rheumatoid
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Dates: during 1990-1999
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Five years ago, when I was bedridden with rheumatoid arthritis, I kept saying to myself, "I have to do something now." But then I thought, "I just have to wait" to get better. After 20 years in the entertainment business, I realize that I don't have the ability to create my own projects as a writer or producer. My talent is interpreting the works of others. I have to wait for good material...
...story of Oliver, the man who was cured by a bumblebee. There was a time when nobody believed Oliver, but when Weil heard the story, he didn't doubt it for a minute. At the time of his cure, Oliver was 64 years old and had been suffering from rheumatoid arthritis since he was in his 30s. His hands were so swollen that he had given up trying to find gloves to fit them. His shoes were two sizes larger than they used to be and seemed to be growing each year. He took up to a dozen different pain...
...that break down old cartilage. But can capsules taken orally do the same thing? Some European doctors are convinced they can, and have been using the supplements since the early 1980s to treat osteoarthritis, the common form of arthritis caused by wear and tear (not to be confused with rheumatoid arthritis, an autoimmune disease). In the U.S. the use of supplements has been limited mostly to treating arthritic dogs and horses...
This week, at the annual meeting of the American College of Rheumatology in Orlando, Florida, scientists will announce not one but three experimental treatments for rheumatoid arthritis. Each is thoroughly modern, using genetically engineered proteins or custom-designed antibodies to combat the disease at its source, blocking the wayward steps leading to the body's self-destruction before further damage occurs...
...three new treatments build on what scientists have learned about the ways in which rheumatoid arthritis works. The problem starts when, for reasons no one fully understands, a few misguided T cells incite other immune-system cells called macrophages to attack the joints. The approach favored by IDEC Pharmaceuticals, a biotech company in San Diego, is to target all active T cells with a custom-made antibody that can temporarily knock the immune cells out of commission. Although this antibody treatment cannot distinguish between normal and misbehaving T cells, the gambit has proved successful. More than half the 122 patients...