Word: rheumatoid
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Dates: during 1990-1999
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...illnesses that comes in more than a hundred varieties. About 20 million people in the U.S., for example, have been diagnosed with osteoarthritis, a degenerative disease in which cartilage that cushions the joints erodes, leading to painful bone-on-bone contact. And 3 million or so more have rheumatoid arthritis, a chronic inflammation of the joints that causes pain, stiffness, swelling and loss of function...
...Boston and several reports in last week's Journal of the American Medical Association. In one study, researchers compared Celebrex, one of the so-called COX-II inhibitors (they attack an enzyme, COX-II, that promotes inflammation) to naproxen, a commonly used NSAID. Both reduced the symptoms of rheumatoid arthritis. But while 26% of the naproxen patients got an ulcer in either the stomach or the small intestine, ulcers struck only 4% to 6% of those taking Celebrex...
Another new drug, called Remicade, approved just a few weeks ago by the FDA, is also the focus of a JAMA report. A medication called methotrexate has long been the treatment of choice for rheumatoid arthritis. It is not an NSAID, so it doesn't cause ulcers--but for many patients it stops working after a while. More than half the people who took Remicade along with methotrexate had at least a 20% reduction in arthritis symptoms, according to the study...
They suspect that the fusillade of 22 injections imposed on children by age six may, alone or in combination, pose significant dangers. Although the evidence is largely anecdotal, some parents charge that inoculations have brought on such disorders as multiple sclerosis, rheumatoid arthritis, chronic fatigue syndrome, diabetes and even autism...
...WRITING CURE Sounds like fiction, but researchers say writing about stressful experiences can improve symptoms in rheumatoid arthritis and asthma patients. And though patients wrote only 20 minutes a day over three consecutive days, about half of them experienced positive effects that seemed to last for months. The study is more evidence that the mind plays an important role in chronic illnesses...