Word: risk
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Dates: during 1980-1989
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...William Castelli, medical director of the Framingham Heart Study, a major research project that for the past 40 years has been following the cardiac history of residents of Framingham, Mass. "A number of us," says Castelli, "feel we can do a much better job of predicting who is at risk of getting heart disease if we look at the LDL and the HDL together...
...counter this confusion, the National Heart, Lung and Blood Institute has for the past three years been running a National Cholesterol Education Program. Last year the program set 200 mg/dl as the amount of total cholesterol (essentially LDL plus HDL) above which individuals are considered to be potentially at risk of developing heart disease; those between 200 and 239 are borderline high risk; anyone with a count of 240 or more may be at high risk. The program suggested that everybody should aim for an LDL count of 130 or lower. However, it did not recommend specific HDL targets...
...Americans measure up to these overall guidelines? Rather badly. The mean cholesterol levels of men over the age of 35 fall well into the borderline-high-risk area. More than a third of American men between the ages of 45 and 64 are in the high-risk category. Because of differences in hormones, premenopausal women run a low risk of developing heart disease. In later years, though, this advantage is lost, and women between 55 and 64 have significantly higher total cholesterol levels than men the same age. The dangers of high readings are evident: the chance of a heart...
Portable analyzers, though, cannot calculate LDL and HDL levels. Even many laboratories have been unable to give consistently accurate counts of HDL. Yet that figure may be the most vital statistic of all in evaluating cardiovascular health in otherwise moderate- or low-risk individuals. Says Dr. Bruce Gordon, associate professor of medicine at Manhattan's Rogosin Institute: "There are a sizable number of people who would be inappropriately treated unless their HDL levels were taken into account...
That's why it took Schmidt and the Phils until Wednesday--the deadline or signing free agents--to agree on a new contract for next season. The Phils didn't want to risk so much money on a player who, although a lock for the Hall of Fame, could hardly enter Cooperstown with the numbers he posted last year...