Word: risked
(lookup in dictionary)
(lookup stats)
Dates: during 2010-2019
Sort By: most recent first
(reverse)
...researchers had hoped that treated patients would lower their risk of heart events because they were given both statin drugs, which curb the liver's production of cholesterol, and a fibrate, which mops up harmful triglycerides in the blood and boosts levels of "good" cholesterol. But all of the volunteers either already suffered from heart disease, or had two or more major risk factors for heart problems - including cigarette smoking, family history and high cholesterol - in addition to diabetes. That may have pushed their diabetes too far along to allow them to see any benefit from the drugs. "This...
...fact, when the trial's investigators looked specifically at diabetics with the highest triglyceride levels, they did see a benefit, with those patients enjoying a lower risk of heart disease than the volunteers with lower triglyceride levels. "Maybe one can say that, at a later stage of the disease, adding a fibrate is not spectacularly beneficial except for this subgroup," says Ganda...
...primary lesson that clinicians can take away from the new findings is that the blind push to lower all risk factors such as blood pressure or cholesterol isn't necessarily healthy, says Dr. Christopher Saudek, director of the diabetes center at Johns Hopkins University. That may even mean resisting the commonsense urge to reduce these measures to recommended or normal range in diabetics patients. "To me, it's a matter of having reasonable and patient-oriented individual targets," he says, "rather than trying to push and push and push just to get lower and lower glucose or blood pressure...
...does not seem to afford significant benefits to diabetics on the whole, Saudek and his colleagues anticipate that going forward physicians and patients will increasingly reintroduce the importance of lifestyle changes, such as improving diet and getting more physically active, for slowing the progression of diabetes and reducing the risk of heart disease. These are therapies that are, after all, proven to work. "These discussions obviously should be going on the whole time, but these studies are one more reminder that medication therapy has its downsides," says Einhorn...
...such things do apparently exist. He's proved himself over a long period. You know what he likes or dislikes. You get him. Maybe you don't always agree; but when you're looking at getting a babysitter and maybe dropping three bills on dinner, you need to minimize risk. For that, the user reviews on Citysearch or Yelp are beyond useless - they're faceless and contradictory - and the same goes for blogs. (Blogs at least sometimes take pictures.) So there, in that whirlwind of trends and fad ingredients and hype and backlash, are a few immense ancient trees, with...