Word: rna
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Dates: during 1970-1979
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Rich and his associates are best known for their research into the structure of transfer RNA, an intermediate component of biosynthesis--the DNA synthesis of proteins in the cell. They have been working together for two years and on this particular project for nine months. Their work will appear in the upcoming issue of the British journal. Nature...
...called phage group, a small band of mostly ex-physicists who decided to use bacteria-eating viruses as a kind of genetic scalpel; the virtually forgotten work of Rockefeller Institute's Oswald Avery; the painstaking efforts of scientists to explain exactly how DNA and its kin, RNA (for ribonucleic acid), performed their magic; and finally the patient toil of Britain's Max Perutz, who unraveled the structure and precise workings of the blood's oxygen-carrying molecule that, in complexity of design, is to DNA what a skyscraper is to a town house...
...coworkers, who have also begun working in the P-3 laboratory at the Biolabs. Doty's group is tackling the vast problem of how genes are turned on and off--using gene splicing as a research tool rather than an end in itself. She has been studying RNA--one of the intermediate steps the cell employs in translating the DNA code--for 22 years. Whereas Gilbert has a definite medical goal pushing him on, Doty must stab in the dark and hope to come up with a lead which will help scientists to understand this most basic of cellular processes...
...that is either highly specific or easily labeled," according to Doty. This is where plasmids and genetic engineering comes in. Once a DNA segment is inserted into a bacterial plasmid, the researchers can grow up a supply of it "overnight." This may be used to identify complementary copies of RNA and to determine where sequence changes occur...
...moping under a sun lamp, dreaming of waves crashing upon white sand and bats cracking against baseballs in Winter Haven, Lakeland and Ft. Lauderdale, you've lost your marbles. And if you think I'm going to spend the week in Lamont, Cabot or Widener, dreaming about Kant, messenger RNA or the Protestant Reformation, or if you have such plans, you never had any marbles to begin with...