Word: role
(lookup in dictionary)
(lookup stats)
Dates: during 2010-2019
Sort By: most recent first
(reverse)
...significant breakthrough, the team successfully identified that a particular gene sequence was associated with differences in telomere length between individuals. What's more, the sequence was clustered near a gene called TERC, which is already known to play a role in the production of an enzyme called telomerase. Telomerase repairs telomeres when they shorten. "That was very exciting for us," says Nilesh Samani, a cardiologist at the University of Leicester who co-led the research, which was published last week in Nature Genetics. "It gave us great confidence that we identified genetic variants on a pathway we already know...
...Samani also says the telomere research offered no quick fixes and that telomere-based treatments were still a long way off. The reason for this is that telomeres - while potentially lowering the risk of heart disease - play a role in the development of cancer cells. "We all probably develop cancer cells that don't get past a few replications because of the effect of normal telomere shortening. If you make cells immortal by allowing them to replenish their telomeres, you may raise the risk of many nasty cancers considerably...
...quietness of the character, but used a light touch. In one scene, he gives his son's blonde, American girlfriend an appreciative once-over when he meets her. Nair says it wasn't in the script, but Khan understood what a little humor can do for a serious role. It was only a brief moment, but it cracked Ashoke's dignified veneer just slightly, letting the audience feel his vulnerability...
...casting her first feature - a cinema verité take on slum life in Bombay - came to the school scouting for talent. "One of the things I'm slightly proud of is kind of discovering Irrfan," says Mira Nair, who cast Khan as a letter writer in Salaam Bombay! His role was edited down to a fleeting appearance, but Nair says that even then, Khan was different. "I was very, very struck by his being in the part rather than acting," she recalls. "He wasn't striving. His striving was invisible...
...More specifically, Justice officials have said he was not forthcoming about his role servicing Igor Olenicoff, the Russian-born, California-based real estate billionaire whom Birkenfeld brought to UBS from Barclays, where Birkenfeld worked before - a charge his lawyers deny. (In 2008, Olenicoff pleaded guilty, paid $52 million in taxes and interest and was sentenced to two years probation and 120 hours of community service. In 2009, Birkenfeld pleaded guilty to one conspiracy count related to tax evasion and in January 2010 began serving a 40-month sentence...