Word: roth
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Dates: during 1990-1999
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...Roth, who has already observed the life-extending effectiveness of caloric restriction in rodents, is conducting similar experiments with primates. Even if they succeed, however, trying to apply the treatment to humans could prove dicey. In a nation of consumers for whom caloric belt tightening can mean little more than a smaller serving of French fries with their bacon cheeseburgers, the belief that people would be willing to reduce what they eat by a full third is probably unrealistic...
Just how this business of swapping food for time works is not entirely clear, but George Roth, molecular physiologist with the National Institute on Aging in Bethesda, Maryland, has some ideas. When animals are placed on caloric restriction, Roth explains, the first thing that happens is that their body temperature drops about 1[degree]C. Lower temperature means a less vigorous metabolism, which means less food is processed. "In order to compensate for the reduction in diet," Roth says, "the animals switch from a growth mode into what can be thought of as a survival mode. They get fewer calories...
...Roth finds this frustrating. "I think caloric restriction could take us beyond a life-span of 80," he says, "maybe even 120. After all, you rarely see a fat centenarian." Given modern dietary habits, however, it may be more practical to find out what part of the metabolic system caloric restriction operates on and then imitate that effect pharmacologically. "Essentially," explains Roth, "we'd use a pill to trick a cell into thinking less food is coming...
Prosser enters this race with several key advantages over opponent Jay Johnson. The Eighth District is strongly Republican: it sent retiring Congressman Toby Roth to Washington eight times and voted for George Bush in the past two presidential elections. Prosser, a long-time Wisconsin politician, is a high-profile crime fighter who helped pass a state Sexual Predator Law. He was named 1996 Legislator of the Year by the National Republican Legislators Association...
...Miss. (3) Carlos J. Moorhead, R-Calif. (27) John T. Myers, R-Ind. (7) L.F. Payne Jr., D-Va. (5) Pete Peterson, D-Fla. (2) James H. Quillen, R-Tenn. (1) Jack Reed, D-R.I. (2) Pat Roberts, R-Kan. (1) Charlie Rose, D-N.C. (7) Toby Roth, R-Wis. (8) Patricia Schroeder, D-Colo. (1) Gerry E. Studds, D-Mass. (10) Robert G. Torricelli, D-N.J. (9) Ray Thornton, D-Ark. (2) Barbara F. Vucanovich, R-Nev. (2) Robert S. Walker, R-Pa. (16) Pat Williams, D-Mont. (at large) Charles Wilson, D-Texas (2) Bill...