Word: roundworm
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Dates: during 2010-2019
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...finding that bodes well for the development of new human antibiotics, Harvard researchers have determined the identity of the trigger that causes roundworm bacteria to excrete virulent substances...
Harvard Medical School Professor Jon Clardy teamed with researchers in the department of biological chemistry and molecular pharmacology to pinpoint the amino acid proline—a component of hemolymph, or insect blood—as the trigger for the transformation of roundworm bacteria from dormant to virulent, eliciting comparisons of the bacteria to Dr. Jekyll and Mr. Hyde...
When normal cells are hijacked by cancer cells, the natural substances are similarly triggered to aid the proliferation of the cancer. Just as the Harvard scientists were searching for the transforming factor in the case of the roundworm, the trigger of how normal cells aid cancer cells in becoming lethal tumors is “the unknown everybody is going after right now in cancer research,” Kalluri said...