Word: rous
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Dates: during 1950-1959
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...Hottest Thing. "Right now," says National Cancer Institute's Heller, "the hottest thing in cancer is research on viruses as possible causes." The Rockefeller Institute's Dr. Peyton Rous showed as long ago as 1911 (his findings were unpopular at the time) that one cancer (sarcoma) in chickens is caused and can be transmitted by a virus. Over the years, viruses were found to cause other tumors in birds and lower animals. But the gap between them and man seemed unbridgeable. Then the University of Minnesota's Dr. John J. Bittner showed that breast cancer in certain...
Quake in the Night. Blue eyes twinkling as brightly as ever at 79, Dr. Rous admitted last week: "I used to quake in the night for fear that I had made an error." One of his colleagues, he recalled, was so sure that cancer was an unfathomable mystery that he said: "That can't have been a tumor if you found the cause of it." Today no line of investigation into the origins of human cancer is being pressed more vigorously than that implicating viruses as at least partly responsible. Though he has never worked with human cancers...
...brilliant young investigator, Dr. Francis Peyton Rous (rhymes with mouse), the discovery proved an embarrassment. Some colleagues smiled tolerantly, but many cancer researchers, even within his own institute, denounced the work as preposterous. "A filterable virus?" Bosh! This would be an infectious agent, and thus cancer, they argued, would be an infectious disease. Rous's experiments, they said, must have been defective. Some critics were not even shaken when Rous went on to find the viruses that caused other types of cancers in fowls and small mammals...
Animal or Chemical? Last week, 48 years after his original preconception-shattering experiments, Peyton Rous stood before an audience in Manhattan to acknowledge a new honor in the string that has been lengthening since 1927: one of the Albert Lasker Awards ($2,500 plus a gold Winged Victory) of the American Public Health Association-one of medicine's brightest "Oscars...
There is no longer any doubt that Rous's experiments were superbly executed and that his conclusions were sound. The Rous sarcoma and many others in a growing family of animal tumors are now known to be caused by viruses, although the definition of viruses (ultramicroscopic particles on the borderline of the animal and chemical kingdoms) may have to be revised to cover them all. It still seems that something more than the virus alone is needed to trigger the outbreak of cancerous growth, e.g., chemical or physical irritation. But the importance of the virus can no longer...