Word: roussell
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Dates: during 1990-1999
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Armed with this knowledge, says Edward Keystone, director of advanced therapeutics in arthritis at Mount Sinai Hospital in Toronto, "we're targeting every element of this disease from start to finish." The new drug Arava, for example, created by the Kansas City, Mo., firm Hoechst Marion Roussel, stops white cells from reproducing. Enbrel, a genetically engineered medication from Seattle-based Immunex, works by sopping up a tumor-killing cytokine called tumor necrosis factor before it can issue its call for reinforcements. The COX-2 inhibitors target prostaglandin production, limiting pain and inflammation. And the blood-filtration device, invented at Cypress...
...Food and Drug Administration might be reluctant to green-light the drug. That's because the FDA's pressure prompted Hoechst-Marion-Roussel to pull probucol from the market two years ago: The drug lowers the body's levels of artery-protecting "good" cholesterol by 40 percent, a definite drawback...
...crashes, wide screen, beautiful color, the cliffs of Capri, the most rapturous music (by Georges Delerue, his violins sawing and soaring like Philip Glass in ecstasy). And, always, pretty women. A Ziegfeld of the Left Bank, Godard reinvented Jean Seberg and discovered Anna Karina, Juliet Berto, Maruschka Detmers, Myriem Roussel, Juliette Binoche, Julie Delpy--glories of Gallic cinema. In Contempt he saves Bardot from cheesecake notoriety. She's smart, sensitive, brutal, doomed...
PARIS: Bowing to boycott threats from American anti-abortion groups, European pharmaceutical giant Hoechst transferred non-U.S. patent rights to the abortion pill RU-486 to one of the doctors who invented it. Although Edouard Sakiz, who headed Roussel Uclaf, the company that lead the development of RU-486 before it was acquired by Hoechst, will market the drug worldwide through a new company, he said he will not do business in the U.S. Once the drug wins approval, it will be distributed by The Population Council, a New York-based non-profit that received the U.S. patent from...
Only a few years ago, it looked as if American women might never have access to RU-486, whose chemical name is mifepristone. It has been available in Europe since 1988, but the French manufacturer, Roussel Uclaf, fearing harassment by militant antiabortionists, refused to market it in the U.S. In 1994, though, the New York City-based Population Council offered to take the heat and acquired the drug's American patent rights. After two years of clinical trials, the organization applied to the FDA for permission to sell the drug. In July an advisory committee recommended approval...