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...Instead, Roussel-UCLAF, the patent holder of the 20-year-old pill, granted sole American distribution rights to the Population Council, a nonprofit organization specializing in reproductive issues, with the understanding that the group would conduct clinical trials and find a manufacturer for the drug. After six years of research and more than a few last-minute panic attacks from would-be manufacturing companies, the moment of reckoning has arrived: The Population Council has concluded a hugely successful drug trial in which 92 percent of the participants achieved a "favorable" outcome and a marketing group, Banco Laboratories, and manufacturer...

Author: /time Magazine | Title: Ready for Battle: The FDA Considers the Fate of RU-486 | 9/26/2000 | See Source »

Armed with this knowledge, says Edward Keystone, director of advanced therapeutics in arthritis at Mount Sinai Hospital in Toronto, "we're targeting every element of this disease from start to finish." The new drug Arava, for example, created by the Kansas City, Mo., firm Hoechst Marion Roussel, stops white cells from reproducing. Enbrel, a genetically engineered medication from Seattle-based Immunex, works by sopping up a tumor-killing cytokine called tumor necrosis factor before it can issue its call for reinforcements. The COX-2 inhibitors target prostaglandin production, limiting pain and inflammation. And the blood-filtration device, invented at Cypress...

Author: /time Magazine | Title: Arthritis Under Arrest | 9/28/1998 | See Source »

...Food and Drug Administration might be reluctant to green-light the drug. That's because the FDA's pressure prompted Hoechst-Marion-Roussel to pull probucol from the market two years ago: The drug lowers the body's levels of artery-protecting "good" cholesterol by 40 percent, a definite drawback...

Author: /time Magazine | Title: Cholesterol Fighter Taken to Heart | 8/7/1997 | See Source »

...crashes, wide screen, beautiful color, the cliffs of Capri, the most rapturous music (by Georges Delerue, his violins sawing and soaring like Philip Glass in ecstasy). And, always, pretty women. A Ziegfeld of the Left Bank, Godard reinvented Jean Seberg and discovered Anna Karina, Juliet Berto, Maruschka Detmers, Myriem Roussel, Juliette Binoche, Julie Delpy--glories of Gallic cinema. In Contempt he saves Bardot from cheesecake notoriety. She's smart, sensitive, brutal, doomed...

Author: /time Magazine | Title: CINEMA: FOR EVER GODARD | 8/4/1997 | See Source »

PARIS: Bowing to boycott threats from American anti-abortion groups, European pharmaceutical giant Hoechst transferred non-U.S. patent rights to the abortion pill RU-486 to one of the doctors who invented it. Although Edouard Sakiz, who headed Roussel Uclaf, the company that lead the development of RU-486 before it was acquired by Hoechst, will market the drug worldwide through a new company, he said he will not do business in the U.S. Once the drug wins approval, it will be distributed by The Population Council, a New York-based non-profit that received the U.S. patent from...

Author: /time Magazine | Title: Hoechst Dumps RU-486 | 4/8/1997 | See Source »

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