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Currently, one major class of drugs that fights AIDS, called RT inhibitors, tries to interfere with RT. These drugs range from...

Author: By Gregory S. Krauss, CRIMSON STAFF WRITER | Title: Researchers Find New Clues to AIDS Virus Replication | 12/1/1998 | See Source »

...mutations in RT--which lead to mutations in HIV--sometimes make these drugs ineffective, said Huifang Huang, a post-doctoral fellow in the Department of Molecular and Celluar Biology who served on the research team...

Author: By Gregory S. Krauss, CRIMSON STAFF WRITER | Title: Researchers Find New Clues to AIDS Virus Replication | 12/1/1998 | See Source »

...group's research, published in an article in Science entitled "Structure of a Covalently Trapped Catalytic Complex of HIV-1 Reverse Transcriptase: Implications for Nucleoside-Analog Drug Resistance," represents years of efforts aimed at understanding RT...

Author: By Gregory S. Krauss, CRIMSON STAFF WRITER | Title: Researchers Find New Clues to AIDS Virus Replication | 12/1/1998 | See Source »

...late 1980's Harrison and colleagues at other schools began uncovering the structure of RT. But until recently, researchers still did not know much about the mechanisms by which RT worked...

Author: By Gregory S. Krauss, CRIMSON STAFF WRITER | Title: Researchers Find New Clues to AIDS Virus Replication | 12/1/1998 | See Source »

According to Harrison, when HIV enters a human cell, it uses RT and RNA to form a new strand of viral DNA. Then this strand is used to make another one,which when joined with the first, forms the fameddouble helix...

Author: By Gregory S. Krauss, CRIMSON STAFF WRITER | Title: Researchers Find New Clues to AIDS Virus Replication | 12/1/1998 | See Source »

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