Word: ruvkun
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Dates: during 2000-2009
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...findings, published by Professor of Genetics Gary Ruvkun in the Oct. 6 issue of the journal Science, suggest that the brain may have a bigger role in controlling aging than was previously thought...
...Ruvkun and other scientists choose to work with the laboratory roundworm, a tiny bacteria-eating soil-dweller, because the sequence of its entire genome is known and its 302-neuron nervous system has been described in detail...
...their recent study, Ruvkun and his colleagues first used genetic tricks to deactivate genes that encode the proteins--known as receptors--that respond to insulin signaling in many worm tissues, creating a group of long-lived individuals...
This result was surprising, according to Ruvkun, because when worms get old they start to show decay all across their body, just as people...