Word: ruvkun
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When Harvard Medical School professor Gary B. Ruvkun started researching the development of roundworms 20 years ago, he had no idea that the tiny genes of their ribonucleic acid—DNA’s chemical cousin—would map out a new field of biology...
...recognition of his work on miRNA, Ruvkun won this year’s Lasker Award for Basic Medical Research—a prize he shares with his fellow researchers, Victor R. Ambros, a professor at the University of Massachusetts Medical School in Worcester, and David Baulcombe, who teaches at the University of Cambridge...
...Ruvkun and his co-recipients found that miRNAs—long regarded as far less versatile players in gene activity—play a significant role in governing growth and development in animals and plants. This discovery could have implications for diseases such as viral infections, heart failure, and cancer, as well as shed light on normal functions like muscle action...
...Ruvkun suggests that with the current understanding of the roundworm’s gene composition, new drugs might be developed to deal with obesity...
...proteins are equally good targets for drug development,” said Ruvkun...