Word: ruzicka
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True to his promise of a month ago that he would soon be able to manufacture the hormone secreted by the testes which accounts for masculinity (TIME, Sept. 2), Dr. Leopold Ruzicka, Swiss chemist, last week announced that his assistants in his Zurich laboratory had just cabled him word of their success. Testosterone is the name of the new hormone. It is related to the male sex hormone, androsterone, found in urine which Dr. Ruzicka previously synthesized. Like androsterone, testosterone is made from the fat (cholesterol) in sheep's wool, but is 25 to 50 times as potent...
Natural testosterone, long anticipated, was discovered in human testicles only last June by Dr. E. Laqueur of Amsterdam. Producing the imitation so soon afterward made Dr. Ruzicka glow with professional pride...
Sheep's Wool & Sex. "We have a positive cure for homosexuality," exclaimed Professor Leopold Ruzicka, a Swiss organic chemist who lectured at the University of Chicago this summer. In 1931 Dr. Adolf Butenandt of Danzig discovered in the urine of men (and some women) the hormone which establishes masculinity in men (and some women). That male sex hormone was named androsterone. Last year Professor Ruzicka manufactured androsterone from cholesterol collected from the grease of sheep's wool. Last June Dr. E. Laqueur of Amsterdam discovered still another, more potent male sex hormone. Professor Ruzicka now expects to make...
Meanwhile doctors over the face of the earth, experimenting with Chemist Ruzicka's artificial androsterone, have told him enough to warrant his claiming: "By the injection of the hormone, normal sex desires can be awakened and will be accompanied by certain physical changes. The hormone, further, can be used in reducing enlargement of the prostate gland; common in elderly...
...pure form the active principles of the endocrine glands. When Chemist Edwin Calvin Kendall of the Mayo Clinic isolated thyroxin, the essence of the thyroid, about 15 years ago, a loud cry of applause arose. Since then other hormones have been refined and analyzed. Last week Professor Leopold Ruzicka of Zurich significantly reported in Nature that he had synthesized the male sex hormone. To get it, this altogether reputable scientist attacked hydroxy-ketone, a substance related to acetone, with dihydrocholesterol which is a derivative of cholesterol found in bile, brains and eggs. Nicely controlled chemical procedure produced a modified hydroxy...