Word: sabin
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...purists, Johns Hopkins University's Dr. David Bodian said that there should be a clear showing, as in the Salk 1954 field trial, based on different paralysis rates among vaccinated and unvaccinated. This was exasperating to both the University of Cincinnati's Dr. Albert B. Sabin and Lederle Laboratories' Dr. Herald R. Cox, developers of two of three U.S. live vaccines. It is an impossible requirement, snapped Dr. Sabin, because by its very nature the oral, weakened virus is designed to multiply in the human digestive tract. It is bound to spread to unvaccinated contacts (especially close...
...Monkey. Both Sabin and Cox asserted that there is enough evidence from millions of oral vaccinations in a score of foreign countries to show that their vaccines are safe and sure.* But each insisted that his own was better than either of its two rivals. (Dr. Sabin has attacked the third vaccine, developed by the Wistar Institute's Dr. Hilary Koprowski, charging that it contains viruses that cause disease in monkeys and might be dangerous for man.) Dr. Sabin gives his vaccine in three separate doses a month apart-one for each main type of polio virus...
Leaders in perfecting live vaccines against polio have been the University of Cincinnati's Dr. Albert B. Sabin (TIME, May 23, 1955), and Dr. Hilary Koprowski. who began the work at Lederle Laboratories, then switched to Philadelphia's Wistar Institute. Dr. Sabin revisited his native Russia in 1956 to report on his early tests, so impressed Soviet medical men that they went to his Cincinnati labs for vaccine samples...
Chumakov began brewing Sabin-type vaccine at the Institute for the Study of Poliomyelitis, a rambling frame building among the railroad yards on Moscow's outskirts. Last week he was readying the world's biggest test of live polio vaccine, had 300 liters on ice-enough for 10 million people. No small operators, Chumakov and colleagues dreamed of immunizing all the Soviet Union's 200 million people regardless of age (600 million doses, since vaccine for one strain of each of polio's three main virus types is given in separate swigs, a month apart). Satellite...
...Sabin-type vaccine got a different type of test in Singapore when it was hit by a polio epidemic last August. British-trained Professor James Hale decided to work with Sabin's Type II vaccine. All the polio occurring was of Type I. If any Type II disease showed up, it would be almost certainly due to faulty vaccine. But while Type II vaccine is supposed to give 100% protection only against Type II disease, it is claimed to give about 60% protection against Type I also. As hoped, Type I disease began to decline sharply...