Word: sabin
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Cincinnati's respected Dr. Albert Sabin (TIME, May 23), long the foremost critic of vaccines made (like Salk's) of inactivated virus, urged that both production and inoculation be stopped until the vaccine can be made consistently safe.* He was supported by men of impressive professional caliber: Nobel Prizewinner John F. Enders of Boston's Children's Medical Center and Dr. William McD. Hammon, an epidemiologist who rubs elbows with Dr. Salk at the University of Pittsburgh...
Cincinnati's Dr. Albert Sabin, outspoken champion of a live-virus vaccine (TIME, May 23), suggested that all three paralysis-causing strains used in the Salk preparation be thrown out. In their place he would put nonvirulent strains, which may be found in nature or "bred" selectively in the laboratory. Knowing that his audience was far from ready to accept live viruses, Dr. Sabin cannily reminded them that these too could be treated with formaldehyde. This would give double protection, and a Swedish researcher is working on such a vaccine right...
...live vaccine safe? Dr. Salk, for one, does not think so. Although the live-virus method has been used successfully in the long-established smallpox and yellow fever vaccines, he believes that the polio virus is too tough and tricky to permit development in safe, nonvimlent form. Dr. Sabin disagrees, thinks it can be done. Growing virus strains of all three types under hothouse conditions, he found some that, when injected into the spinal cords of chimpanzees, produced no paralysis. All they did was to stimulate the animals to produce antibodies against any future invading polio virus. And these antibodies...
...more susceptible than the chimpanzees to the desired kind of infection. They did not get sick in any apparent way Yet the virus multiplied in their digestive tracts, boosted their antibody levels and was excreted in the stools for one to twelve weeks. It was in this connection Dr. Sabin reported his only setback...
Taking a long leap into a hypothetical future, Dr. Sabin foresaw a day when babies will have their throats swabbed with his vaccine before they are six months old, while they are still protected by inherited antibodies. Or, others sug gest, people of any age could get tem porary immunity from a single Salk shot then parlay it into virtual lifetime immunity with a Sabin swab...