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...series of experiments, scientists at Purdue University compared weight gain and eating habits in rats whose diets were supplemented with sweetened food containing either zero-calorie saccharin or sugar. The report, published in Behavioral Neuroscience, presents some counterintuitive findings: Animals fed with artificially sweetened yogurt over a two-week period consumed more calories and gained more weight - mostly in the form of fat - than animals eating yogurt flavored with glucose, a natural, high-calorie sweetener. It's a continuation of work the Purdue group began in 2004, when they reported that animals consuming saccharin-sweetened liquids and snacks tended...

Author: /time Magazine | Title: Can Sugar Substitutes Make You Fat? | 2/10/2008 | See Source »

What they mean is that like Pavlov's dog, trained to salivate at the sound of a bell, animals are similarly trained to anticipate lots of calories when they taste something sweet - in nature, sweet foods are usually loaded with calories. When an animal eats a saccharin-flavored food with no calories, however - disrupting the sweetness and calorie link - the animal tends to eat more and gain more weight, the new study shows. The study was even able to document at the physiological level that animals given artificial sweeteners responded differently to their food than those eating high-calorie sweetened...

Author: /time Magazine | Title: Can Sugar Substitutes Make You Fat? | 2/10/2008 | See Source »

...Simon answers as meekly as possible. The light is about to change and the car inches forward towards the onramp. “Get in,” the driver says, her voice cracking. A plastic blowfish bath toy swings from the rearview mirror. The car smells like saccharin, like a new synthetic interior mixed with a kid come straight off the playground. The doughy-faced, front-seat passenger introduces us first to her 10-year-old daughter, sitting next to Simon, and then to the visibly nervous driver in front of me. While Simon tries to make the hosts...

Author: By Francesca M. Mari, | Title: The Hitchhiking Type | 7/13/2006 | See Source »

Cutting out sugar sounds like a winning strategy for a country that's 66% overweight or obese, but are sugar substitutes in fact good for you? The scientific record is less than absolute. Past studies of saccharin and aspartame, packaged as Sweet'n Low and Equal, respectively, suggested that large doses could cause cancer in rats, although human studies have shown no such link. The Food and Drug Administration says these high-intensity sweeteners--along with sucralose (Splenda)--pose no threat to human health. Most nutrition experts are willing to go along with that--with caveats. "I suspect that...

Author: /time Magazine | Title: How Sweet It Isn't | 6/11/2006 | See Source »

...Think diet soda helps you lose weight? Think again. According to a study in the International Journal of Obesity, artificially sweetened, low-calorie foods can thwart your ability to regulate how much you eat?if you are a rat, that is. Researchers found that lab animals sometimes fed saccharin-sweetened liquid consumed more food than did rats given an equally sweet but always high-calorie liquid. (Rats given a high-cal supplement the consistency of milk also gained more weight than did rats fed a thicker, pudding-like substance.) The study's authors think the same phenomenon may hold true...

Author: /time Magazine | Title: Your Health | 9/13/2004 | See Source »

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