Word: safe
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Dates: during 1950-1959
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...spokesmen disclosed how close the U.S. had been to unimaginable disaster. Dr. William H. Sebrell Jr., director of the PHS's National Institutes of Health, testifying before a House committee, in effect answered the question that for a month had haunted U.S. parents: was the Salk vaccine safe? Answer: no, not under testing procedures so far used. Sebrell admitted that the safety tests originally developed for the 1955 Salk vaccine had proved to be "less than satisfactory," and also that the margin of safety built into the minimum standards was "no longer dependable...
From all sides he had heard manufacturers report failures "for no apparent reason" in the process of inactivating the virus, i.e., making a safe vaccine. A manufacturing rival of Cutter said with commendable candor: "There is absolutely nothing to indicate that Cutter testing was not adequate. If that's so, then what happened to them could have happened...
...Safe, Safer? The more the authorities congratulated themselves on the new tests, the more (by implication, at least) did they condemn the old. PHS's Dr. James Shannon said that the revisions provide "more frequent and sensitive testing on what we now believe to be a more rational basis." Surgeon General Leonard Scheele called it "making a safe vaccine safer...
...original "safe" vaccine had been followed by 113 cases of polio among the vaccinated. Last week an additional ten were among Cutter subjects. But because four full weeks had passed since Cutter inoculations were stopped, and the incubation period for polio is rarely more than 31 days, it seemed more likely that in the new Cutter cases the trouble was not defective vaccine, but the absence of a second shot in time to prevent a natural polio infection...
...hold clinics in the schools during vacations, though officials fully recognized that there would be wholesale absenteeism. Parents were relaxing their pressure to get vaccine. The pressure now took on a new form: the big question across the U.S. last week was whether even the rechecked vaccine is safe...