Word: salk
(lookup in dictionary)
(lookup stats)
Dates: during 1950-1959
Sort By: most recent first
(reverse)
...Salk vaccine of 1954 was safe, as was proved by more than 400,000 inoculations with only 71 subsequent cases of paralytic polio (none of them attributable to the vaccine). But the Salk vaccine of 1955 is not the same as that of 1954. A big difference is in the testing procedures...
...Tests Work. On the face of it, nothing could be more thorough than the inactivation and testing procedures worked out by Dr. Jonas E. Salk and adopted as standard by the Public Health Service. To "kill" or (more precisely) inactivate the virus, a formaldehyde solution is added to it. Typically, one cubic centimeter of this is enough to kill the virus in 4,000 cc. of culture. After about , three days only one particle out of 10 million will be left active. In an effort to eliminate even this last particle, the process is continued for as long...
Last year's vaccine was triple-tested* in the manufacturer's own labs, Dr. Salk's labs at the University of Pittsburgh, and the U.S. Laboratory of Biologies Control...
While virologists were still trying to decide whether Dr. Salk's "killed" virus vaccine was safe, or how it could be made safer (see above), other experts argued that the killed-virus idea should be abandoned altogether. Leader of this school...
...live vaccine safe? Dr. Salk, for one, does not think so. Although the live-virus method has been used successfully in the long-established smallpox and yellow fever vaccines, he believes that the polio virus is too tough and tricky to permit development in safe, nonvimlent form. Dr. Sabin disagrees, thinks it can be done. Growing virus strains of all three types under hothouse conditions, he found some that, when injected into the spinal cords of chimpanzees, produced no paralysis. All they did was to stimulate the animals to produce antibodies against any future invading polio virus. And these antibodies...