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...Salk, Sabin, and other authorities and organizations had disagreed on the relative merits of the vaccines, but the dispute remained subdued until the AMA House of Delegates state, in March, 1961, that "the persistence of immunity induced by the oral [Sabin] vaccine may be of much longer duration than is the case with Salk vaccine and, in fact, the persistence of immunity may conceivably approach that induced by natural infection in type, degree, and duration." And while the AMA urged wider use of Salk injections until Sabin was licensed, it noted that the Sabin protects against both paralytic...

Author: By Peter Cummings, | Title: Salk and Sabin | 3/2/1963 | See Source »

...Salk protested the AMA statement, accusing it of "misinformation and misleading references," and when he asked why he was not consulted in the matter, the AMA replied that it "wanted experts who were not protagonists." Salk expressed the fear that Sabin protection would simply reintroduce the live virus into the human environment, but Dr. Spring, secretary of the House of Delegates, rejoined that "everyone should get them as extra protection... In our opinion, the more vaccination the safer you are. This does not imply that the Salk vaccine is useless, but it is not perfect and at present a booster...

Author: By Peter Cummings, | Title: Salk and Sabin | 3/2/1963 | See Source »

...check the possibility that the Sabin virus had caused the disease. In the U.S. eleven such cases were reported after 38,000,000 inoculations, and the victims had all exhibited symptoms after the use of Type III vaccine. In 1955 a similar situation occurred with 67 polio outbreaks after Salk treatment. Subsequent investigations revealed faulty production of "dead" virus by Cutter Laboratories. (Cutter later had to pay over a million dollars in damages...

Author: By Peter Cummings, | Title: Salk and Sabin | 3/2/1963 | See Source »

...recommended that communities withhold Type III from adults, yet at the same time urged that all types be given to children. But many Communities decided to stop all Sabin activities and allowed their vaccination programs to flounder despite PHS pleas for more inoculations. These events elicited remarks from Dr. Salk in praise of his vaccine, protests from Sabin, a statement from New York Health Commissioner Hilleboe that he would only permit use of the Salk preparation, and a remark from Dr. Eichenwald of Cornell's New York Hospital insisting that oral vaccine "is safer and more effective against polio than...

Author: By Peter Cummings, | Title: Salk and Sabin | 3/2/1963 | See Source »

...order to properly appraise the value of the two vaccines, one should examine their differences. Both are made from live polio viruses, cultured in test tubes on monkey kidney tissue. In the Salk process, the viruses are heated in formalin, killing them and making them safe for injection into the human blood stream. Fourteen days after the first shot, antibodies appear in the blood, giving a slight amount of protection against all three types of polio virus. Then a booster shot is administered and seven months later another booster, both raising the antibody level. A year later a fourth injection...

Author: By Peter Cummings, | Title: Salk and Sabin | 3/2/1963 | See Source »

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