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...Tests Work. On the face of it, nothing could be more thorough than the inactivation and testing procedures worked out by Dr. Jonas E. Salk and adopted as standard by the Public Health Service. To "kill" or (more precisely) inactivate the virus, a formaldehyde solution is added to it. Typically, one cubic centimeter of this is enough to kill the virus in 4,000 cc. of culture. After about , three days only one particle out of 10 million will be left active. In an effort to eliminate even this last particle, the process is continued for as long...

Author: /time Magazine | Title: Medicine: The Dangerous Short Cut | 5/23/1955 | See Source »

Last year's vaccine was triple-tested* in the manufacturer's own labs, Dr. Salk's labs at the University of Pittsburgh, and the U.S. Laboratory of Biologies Control...

Author: /time Magazine | Title: Medicine: The Dangerous Short Cut | 5/23/1955 | See Source »

While virologists were still trying to decide whether Dr. Salk's "killed" virus vaccine was safe, or how it could be made safer (see above), other experts argued that the killed-virus idea should be abandoned altogether. Leader of this school...

Author: /time Magazine | Title: Medicine: Next: Live Vaccine? | 5/23/1955 | See Source »

...live vaccine safe? Dr. Salk, for one, does not think so. Although the live-virus method has been used successfully in the long-established smallpox and yellow fever vaccines, he believes that the polio virus is too tough and tricky to permit development in safe, nonvimlent form. Dr. Sabin disagrees, thinks it can be done. Growing virus strains of all three types under hothouse conditions, he found some that, when injected into the spinal cords of chimpanzees, produced no paralysis. All they did was to stimulate the animals to produce antibodies against any future invading polio virus. And these antibodies...

Author: /time Magazine | Title: Medicine: Next: Live Vaccine? | 5/23/1955 | See Source »

...into a hypothetical future, Dr. Sabin foresaw a day when babies will have their throats swabbed with his vaccine before they are six months old, while they are still protected by inherited antibodies. Or, others sug gest, people of any age could get tem porary immunity from a single Salk shot then parlay it into virtual lifetime immunity with a Sabin swab...

Author: /time Magazine | Title: Medicine: Next: Live Vaccine? | 5/23/1955 | See Source »

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