Word: salmone
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Researchers have long been frustrated by their inability to get cancer cells from patients' tumors to grow rapidly in culture. But the Arizona team, led by Dr. Sydney Salmon and Cell Biologist Anne Hamburger, discovered three years ago that by "conditioning" culture medium with spleen cells taken from mice prone to cancer, they can grow tumor cells from people with common forms of cancer. (The mouse cells apparently produce some yet unidentified factor that supports the growth of certain human cancer cells.) According to Salmon, the cancer cells that thrive and form colonies in the laboratory's plastic...
...main value of the laboratory test, says Salmon, is that it can help the physician plan individual courses of treatment. For example, only 20% of people with cancer of the colon or rectum respond to the drug fluorouracil; the other 80% suffer needlessly from the drug's toxic effects. The new technique may have another benefit: it could be used to evaluate new anticancer drugs without endangering cancer patients...
...researchers stress that at least three years will be needed to verify and refine the technique. Says Salmon: "This is not now a clinical test available in every hospital. Until it has had adequate testing, it should be considered only a promising research tool." Still, that promise is exciting. A Journal editorial accompanying the paper notes that "an effective and practical predictive test for antitumor agents would have a profound effect on the treatment of cancer...
...tiny Haines, Alaska (pop. 1,366), some 200 Canadians were suddenly disqualified last week from the annual Salmon Derby. Exclaimed Contest Chairman David Olerud, owner of a sporting goods store: "My God, they're our neighbors!" In Atlantic and Pacific coastal waters, about 100 commercial fishing boats-60 or so American-withdrew in the direction of their home ports. Both countries then set their diplomats to thrashing out the issue that had divided them: the right to fish off each other's coast...
Besides boundary lines, the dispute involves conservation. The U.S. last year gave Canadians temporarily increased access to U.S. West Coast salmon grounds, on condition that Canada close its Swiftsure Bank fishing area off British Columbia, where much of the U.S. salmon catch matures, from April 15 until June 14. Canada dawdled in honoring the proviso until May 15. On the East Coast, Canada demanded that the U.S. cut back its catch of scallops, cod, pollock and haddock on the Georges Bank to match quotas imposed by Ottawa on its own fishermen. State Department negotiators declared that Washington did not have...