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...real shock. - With reporting by Jeff Israely Alternative Medicine What's the remedy for growing pains in the global pharmaceutical sector? For Novartis, it's generic: the Swiss firm last week swallowed Germany's Hexal and America's Eon Labs for $8.4 billion, forging them into its existing Sandoz unit to create the world's largest manufacturer of off-patent, copycat drugs. A slide in blockbuster drug approvals in recent years - combined with the expiration of patents protecting a wave of branded drugs introduced in the '80s - has helped make generics big business. Government encouragement of the sector means...
Painter Paul Stopforth's work depicts the suffering that resulted from the South African policy of apartheid. He has had pieces featured in the Creiger Dane Gallery in Boston; the Johannesburg Art Gallery, Market Gallery, and Everard Read Gallery in Johannesburg; and Gallerie Sandoz in Paris...
BASEL, Switzerland: A year after its rivals Ciba Geigy and Sandoz combined to create the world's largest drug company just across town, Roche Holding is looking to catch up. Monday, the Swiss giant announced it will buy holding company Corange Inc. for $11 billion in a deal that will boost Roche's drug operations from tenth place to sixth in the worldwide medical diagnostics market. Roche will assume Corange's holdings in Germany's Boehringer Mannheim, a market leader in cardiovascular and cancer treatments. It will also gain an 84.2 percent stake in DePuy, a Warsaw, Indiana-based manufacturer...
...most perplexing and devastating of all mental illnesses, was an early success story. After several decades as a hopeless research backwater, the schizophrenia field was reborn in 1989, when the U.S. Food and Drug Administration approved a remarkable drug, clozapine (brand name: Clozaril). Made by the Swiss pharmaceutical firm Sandoz, Clozaril was aimed at patients who did not benefit from other drugs. While traditional antipsychotic drugs such as chlorpromazine (Thorazine) and haloperidol (Haldol) work by blocking dopamine receptors, Clozaril appears to bind to serotonin receptors as well. "It is what we call a dirty drug," says Mount Sinai's Davis...
...gene-therapy concerns that seem to show the most promise. "Many, many companies have scrambled to get into the race," notes Ed Hurwitz, an analyst for Robertson, Stephens & Co. The list of recent mergers, as Hurwitz ticks them off, reads like a Who's Who of biotechnology: "Sandoz buys Genetics Institute. Chiron buys Viagene. Bristol Myers makes a big investment in Somatix. Merck makes a big investment in Vical. Rhone-Poulenc invests in Applied Immune Sciences and several other gene-therapy companies...