Word: sangers
(lookup in dictionary)
(lookup stats)
Dates: all
Sort By: most recent first
(reverse)
Secret of Insulin. Led by a man thumping a small drum, a joyful group gathered in a Cambridge University lab to celebrate with champagne when word came that this year's chemistry prize had gone to British Chemist Frederick Sanger. A fellow at King's College, Sanger is attacking the mystery of life from another chemical angle. In 1954 Sanger announced that after ten years of work, he and a small group of colleagues had determined the structure of the insulin molecule. Their achievement did not result in cheaper or better insulin for the world's diabetics...
Proteins are enormously complicated molecules, and until Sanger's work on insulin, no one had ever been able to determine the structure of even the simplest of them. Chemists have known for many years that protein molecules are made of amino acids (nitrogen-containing organic acids) strung together in long chains or cables. By various kinds of rough treatment, the chemists could separate and count the amino acid building blocks. But this did not reveal their structural plan...
...Sanger tried treating the insulin molecule gently, succeeded in breaking it into large chunks. He separated the fragments and labeled the amino acids on their ends by making them combine with a material called DNP (for dinitropheny). When he broke the fragments into smaller fragments, the amino acids that had been in the end positions were stained yellow with DNP. There are 51 amino acid units in insulin, a comparatively simple protein. But Sanger's patience and skill eventually found the place of each in the long chain. Then he reassembled the fragments and learned how the chain...
...Chicago's La Salle National Bank, "the rise in delinquencies and repossessions was just not alarming at all." By prodding the creditor to be more cautious in his lending and thus weeding out many a weak credit risk, the recession actually im proved collections in some places. Sanger Bros. Department Store in Dallas and one of San Francisco's biggest department stores reported that collections were better during the recession than before it. Said Emil J. Seliga, president of Chicago's Talman Federal Savings and Loan Association: "The line of delinquencies this year is no more than...
...that sometimes strays too far ahead of or behind the layman, and an overexposure of Huntsville's Spaceman Wernher von Braun. But it already shows improvement. For future numbers it has lined up articles from such experts as Air Force Balloonist Lt. Col. David Simons and Dr. Eugen Sanger. director of West Germany's Institute of Jet Propulsion Physics in Stuttgart...