Word: sarafem
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Dates: during 2000-2009
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...PMDD sounds a lot like major depression, that's because the symptoms are very similar. So it's not surprising that standard antidepressants can help. In July 2000, the agency approved the antidepressant fluoxetine (Sarafem) to treat PMDD. Now sertraline (Zoloft) has also been given the nod largely on the strength of Yonkers' study of 200 women with PMDD. That research, first published in the Journal of the American Medical Association, showed Zoloft to be significantly more effective than a sugar pill...
...could be that other therapies--hormones, say, or even psychotherapy--work just as well as Zoloft and Sarafem. But as Yonkers points out, they have not been as carefully studied as the drugs have. And that's good enough for her. "If a patient came into my office with PMDD," she says, "I would likely prescribe medications almost immediately as a first-line therapy...
Still, most psychiatrists see increased use of the new breed of antidepressants--which includes Paxil, Zoloft and Sarafem--as a positive development. Clinical depression, as Andrea Yates's case reminds us, is a dangerous illness that may drive mothers to kill their babies, fathers to commit suicide and schoolchildren to start shooting their classmates. Most depression in the U.S., says Dr. Darrel Regier of the American Psychiatric Association, still goes untreated. If you or someone you love is suffering crying spells, feeling inappropriately guilty, thinking about suicide or having trouble eating or sleeping, don't ignore the symptoms. You should...
...Lilly is remarketing Prozac under the name Sarafem to treat...
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