Word: sarcoma
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Dates: during 1930-1939
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Following this lead, they X-rayed the tumors of 82 mice infected with a deadly form of mouse cancer known as sarcoma 180. Then they injected into the tumors small amounts of sterile, distilled water several times a day for three to six days. Results: small doses of X-rays, when followed by water, produced an unusually strong effect. Large doses of over 1,000 Roentgen units, when followed by water, completely destroyed all the mouse tumors. When the scientists omitted the X-rays, tried only water, the cancer cells did not die-only the combination worked...
Died. Johnny English, 14, who was kept alive during a critical period of his illness last summer by his hopes of a victory for the Chicago Cubs in the World Series; of neurogenic sarcoma (nerve cancer); in Chicago. Told of the fourth straight defeat of the Cubs last fall, he replied: "Well, you can't always...
Denied the use of human subjects, researchers make most of their cancer experiments on animals. One vicious type of animal cancer-"mouse sarcoma 180"-is highly resistant to such ordinary methods of treatment as radium and X-ray therapy. In very few cases does it dry up and disappear spontaneously. More important, mouse sarcoma 180 is a reliable subject on which to test the effectiveness of various treatments for human cancer...
Casting about for something new with which to attack mouse sarcoma 180. Dr. Richard Lewisohn of New York City's Mount Sinai Hospital decided to try spleen extract. The functions of the spleen, an organ in the upper left abdomen, are not wholly understood but one of them is to disintegrate red blood corpuscles and set free their hemoglobin. It has been observed that when bits of cancer are transported by the bloodstream to colonize elsewhere in the body, the spleen is seldom affected. Spleen extract had been tried against cancer before, without success. Dr. Lewisohn decided that...
...took 281 healthy white mice, implanted cancers under their right armpits by injections of tumor particles of mouse sarcoma 180. The spleen extract which he prepared to use was in high concentration. In most of the mice, hemorrhage then occurred at the cancer site. This was soon covered by a scab which in time was thrown off and the wound eventually healed. The cancer had disappeared, leaving no trace except a slight sparseness of hair over the region it once occupied. Five months after treatment there were no recurrences. In Surgery, Gynecology & Obstetrics last week Dr. Lewisohn gave the percentage...