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Depressed STAR*D patients who were classified for inclusion had no more than one general medical condition (like, say, heart disease) and no more than one additional primary psychiatric disorder besides depression. All patients with multiple comorbidities - along with anyone whose depression had lasted more than two years - were excluded. Once the authors crunched all the numbers, they found that only 22% of STAR*D patients met entry criteria for a conventional antidepressant trial...

Author: /time Magazine | Title: Why Antidepressants Don't Live Up to the Hype | 5/6/2009 | See Source »

...Wisniewski, the lead author of the new study, cautions against interpreting the results as an indictment against greedy drug companies eager to exclude difficult patients in order to show better results. "If the population in a [clinical] trial were more representative, that would come at a cost," he says. Researchers expect a certain number of bad reactions during clinical trials; some of these reactions can cause serious medical problems. If patients enter a trial with multiple complications - if they are, say, not only depressed, but also cocaine-addicted, hypertensive and diabetic - you dramatically increase the chances of adverse side effects...

Author: /time Magazine | Title: Why Antidepressants Don't Live Up to the Hype | 5/6/2009 | See Source »

Some public-health experts say this kind of user-fueled data-tracking may start to help government health officials' efforts to recognize outbreaks. Real-time warnings would allow authorities to stay well ahead of potential pandemics, prepare local populations with appropriate prevention and treatment, and reduce overall illness and deaths. The Google Flu Trends service, which was launched in the U.S. in collaboration with the Centers for Disease Control and Prevention (CDC), is now working with Mexican officials to track search trends in that country. The goal is to help authorities discern whether and where the disease is spreading, getting...

Author: /time Magazine | Title: Is Google Any Help in Tracking an Epidemic? | 5/6/2009 | See Source »

...Sessions' colleagues, for the most part, say he is a changed man. Senator Arlen Specter, whose defection to the Democratic Party opened the door for Sessions to move up, bent over backward on Tuesday to compliment the Alabaman, even though Specter was on the committee in 1986 and voted against Sessions at the time. "My vote against candidate Sessions for the federal court was a mistake," Specter told reporters on Capitol Hill, "because I have since found that Senator Sessions is egalitarian." Echoed Senator Chuck Grassley, an Iowa Republican and another long-term member of the committee, "The reason...

Author: /time Magazine | Title: Sessions Could Make Obama's Supreme Court Fight Tougher | 5/6/2009 | See Source »

...Sherzai is no white knight, his candidacy would have lent the election greater legitimacy. It would have given Afghans a chance to get fully involved in the election process, to discuss policies and platforms. Now Afghans are deprived of at least the perception of choice, and of having a say in their future...

Author: /time Magazine | Title: With a Rival's Withdrawal, Karzai's Path to Re-Election Eased | 5/6/2009 | See Source »

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