Word: scadden
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...principal investigator Dr. David T. Scadden of the Harvard Stem Cell Institute, the team of researchers has succeeded in refuting the common notion that cancer emerges from the mutations of a single cell...
...Cancer is thought to be a process by which a cell accumulates a series of genetic injuries in a multi-step process,” Scadden said. “Our model says that one of those steps can occur in a neighboring cell...
...Stem cells maintain our tissues and get their signals from their environment,” Scadden said. “We just happened upon this finding that in fact abnormal signals can not just prevent stem cells from functioning normally, but can change the whole system...
Researchers are already conducting follow-up research to continue and build upon this discovery. Because the model was conducted on mice, and thus has not yet been proven on humans, Scadden said the team of researchers is now “examining the cellular setting of patients with these human blood cancers...
...partly due to the efforts of a professor seeking to establish strong connections with his students that convinced Lambert to commit to HDRB. After taking the Freshman Seminar “Blood: From Gory to Glory” with Professor David T. Scadden, co-director of HSCI, she was impressed by the lab work that Scadden showed her class. On one occasion, they were able to watch as a mouse —irradiated to the brink of death was injected with stem cells—two weeks later, they returned to find the same mouse, up and running...