Word: schizophrenia
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Dates: during 2010-2019
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Using his expertise in the areas of medical anthropology and psychiatry, Kleinman pointed to various cases of stigmatization in China. People suffering from schizophrenia, HIV/AIDS, leprosy, or epilepsy often face social marginalization because of their illnesses...
Researchers discovered the first antidepressants purely by chance in the 1950s. Seeking a treatment for schizophrenia, scientists at the Munsterlingen asylum in Switzerland found that a drug that tweaked the balance of the brain's neurotransmitters - the chemicals that control mood, pain and other sensations - sent patients into bouts of euphoria. For schizophrenics, of course, that only made their condition worse. But researchers soon realized it made their pill perfect for patients with depression. On first trying it in 1955, some patients found themselves newly sociable and energetic and called the drug a "miracle cure." The drug, called imipramine...
...epigenetic drugs that are thought to work at least in part by stimulating tumor-suppressor genes that disease has silenced. The great hope for ongoing epigenetic research is that with the flick of a biochemical switch, we could tell genes that play a role in many diseases - including cancer, schizophrenia, autism, Alzheimer's, diabetes and many others - to lie dormant. We could, at long last, have a trump card to play against Darwin...