Word: schizophrenia
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...changes might account for the adolescent behaviors so familiar to parents: emotional outbursts, reckless risk taking and rule breaking, and the impassioned pursuit of sex, drugs and rock 'n' roll. Some experts believe the structural changes seen at adolescence may explain the timing of such major mental illnesses as schizophrenia and bipolar disorder. These diseases typically begin in adolescence and contribute to the high rate of teen suicide. Increasingly, the wild conduct once blamed on "raging hormones" is being seen as the by-product of two factors: a surfeit of hormones, yes, but also a paucity of the cognitive controls...
...their fertility begins to decline relatively early - around age 24, six years or so before women's. Historically, infertility has been seen as a female issue, as has the increased risk of Down syndrome and other birth defects, but studies now also link higher rates of autism, schizophrenia and Down syndrome in children born to older fathers. A recent paper by researchers at Sweden's Karolinska Institute found that the risk of bipolar disorder in children increased with paternal age, particularly in children born to men age 55 or older...
...effects of other age-related diseases like diabetes, which is associated with erectile dysfunction and lower levels of testosterone. But researchers think that genetic factors may be behind the link between paternal age and a child's risk of bipolar disorder and psychiatric disorders like autism and schizophrenia, whose origins are increasingly being attributed to DNA. Although sperm may be no more than 90 days old, the cells that make sperm may be subject to increasing DNA mutations as men age, affecting the quality of the sperm they produce...
...Broads, the institute has received one other large gift: a $100 million donation in March 2007 from the Stanley Medical Research Institute to create a new center to study psychiatric disease, a move that backers said would jump-start the search for the genetic basis of bipolar disorder and schizophrenia. The Stanley Institute gift was the largest ever given for psychiatric disease research. Since the genomic powerhouse was created several years ago, Broad said that it has grown to include a community of more than 1,200 of scientists from across MIT, Harvard, and Harvard’s 17 affiliated...
...Broads, the institute has received one other large gift: a $100 million donation in March 2007 from the Stanley Medical Research Institute to create a new center to study psychiatric disease, a move that backers said would jump-start the search for the genetic basis of bipolar disorder and schizophrenia. The Stanley Institute gift was the largest ever given for psychiatric disease research...