Word: schwan
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...post-Vioxx era, agencies like the U.S. Food and Drug Administration (FDA) are also requiring more and more testing. That has led many firms to consult regulators much earlier in the R&D process. "You must align expectations as early as you can with the FDA," Roche CEO Severin Schwan says. "It leads to a much more efficient, effective use of resources on both sides...
...combat soaring costs, Roche also plans to create more customized drugs and redesign the way it develops them. At the center of this push is the company's diagnostics unit, which Schwan oversaw before taking on the top job last year. Perhaps more than any of its rivals, Roche sees diagnostic machines and test kits as crucial to assessing and treating disease in the future. That belief, in turn, has led to a laser-sharp focus on "personalized medicine." So, for example, an oncologist will use a genetic test to pinpoint the exact kind of cancer her patient...
When the Alnylam deal was announced in July 2007, Schwan quipped that it could become Roche's "second Genentech." In his wildest dreams. With a market cap of $95 billion, Genentech--of which Roche has owned a 55% majority stake since 1990--has produced some of the most cutting-edge best sellers on the pharmaceutical market today. Its pipeline remains one of the industry's most promising. In the past, Roche always applied a light touch to this golden goose, but this summer it became too tempting for Schwan. On July 21, in what will probably amount to a hostile...
...Schwan argues that taking over Genentech will, in fact, allow it to focus even more on the science at its core. But he also recognizes the need for freedom. "Genentech research needs to stay autonomous," Schwan says. "That is the key to preserving the specific culture they have...
That was, until Nov. 15, 2002, when he was fired after 15 seasons, 306 wins, nine NCAA tournament appearances—and one afternoon game in which he responded, either justifiably or inappropriately (depending on your take), to physical aggression from Zach Schwan, one of his players...