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Molecular biologists still know so little about the human genome, in fact, that even with some 85% of the sequence published on the HGP's GenBank website for every scientist in the world to see, nobody has even a ballpark figure for how many genes humans have. Before this week, the betting ranged from as few as 28,000 to as many as 140,000. Now it looks more like...

Author: /time Magazine | Title: The Genome Is Mapped. Now What? | 7/3/2000 | See Source »

...scientist whose work has been transformed by genomics is Dr. David Altshuler, an endocrinologist at Massachusetts General Hospital who does research at M.I.T.'s Whitehead Institute. A diabetes expert, he wanted to learn more about a gene known to be involved in adult-onset (Type II) diabetes and obesity. He knew that the gene was about 100,000 chemical letters--or base pairs--long, and that only about 2,000 of those directed the production of a protein...

Author: /time Magazine | Title: The Genome Is Mapped. Now What? | 7/3/2000 | See Source »

Another Whitehead scientist, oncologist Dr. Todd Golub, is trying to improve on the primitive techniques doctors use to guide their fight against cancer. Currently, pathologists use the location of a tumor in the patient's body and its appearance under a microscope to determine what sort of malignancy is involved. It works often--but not always. Melanoma, for example, starts out as a skin cancer but may end up in the lung or breast, where it can be much more damaging than primary lung or breast cancer...

Author: /time Magazine | Title: The Genome Is Mapped. Now What? | 7/3/2000 | See Source »

...last April, Aristides (Ari) Patrinos, a scientist at the Department of Energy who directs that agency's share of the Human Genome Project, got a call from Francis Collins, director of the National Institutes of Health's National Human Genome Research Institute and the project's unofficial head. "Let's try it," said Collins--and at those words Patrinos knew that a longstanding scientific feud finally had a chance of being resolved. For months, Collins had been under pressure to hammer out his differences with J. Craig Venter, the prickly CEO of Celera Genomics, which was running its own independent...

Author: /time Magazine | Title: The Race Is Over | 7/3/2000 | See Source »

...just worried about "sensitive" nations; it concluded that scientists traveling to countries like Britain and France are at risk too, and recommended that all travel requests by, scientists be reviewed by the DOE. Maybe every time a scientist wants to leave the country, he should have to take Richardson along...

Author: /time Magazine | Title: New DOE Dilemma: Sex-Mad Scientists | 6/25/2000 | See Source »

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