Word: scolnick
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...Broad Institute, a three-year-old joint venture between Harvard and MIT. “There’s no understanding of the causes of these diseases, and that needs to come from collaboration between clinical people and those in neuroscience and genetics,” said Edward Scolnick ’61, who directs the institute’s Psychiatry Initiative and will head the new center. “We can take that on now in a way that would have been impossible without the Stanley grant.” The money will be donated over...
...which it was first discovered). In about 30% of cancers, the RAS protein is stuck in an "on" position, mindlessly ordering the cell to divide again and again. It plays a role in 90% of pancreatic cancers, 50% of colon cancers and 25% of lung cancers. Dr. Edward Scolnick discovered the RAS gene in rats while working at the National Cancer Institute in 1978. Now president of Merck Research Laboratories, he is overseeing the development of a drug that stops the RAS protein from sending its malignant message. Several other big drug companies, including Bristol-Myers Squibb, Johnson & Johnson...
...cancer. Cancer is a complicated disease. Tumors usually are made up of different types of cells, expressing different genes, sensitive to different growth factors and therefore responding to different drugs. "When you are trying to kill cancer cells, you're always likely to need combination treatment," says Merck's Scolnick. Like AIDS treatments, the new generation of cancer drugs will need to be combined with older drugs and possibly with one another to be most effective...
...Scolnick, who is president of Merck Research Laboratories, said these complaints should not detract from the industries' important contributions to science and world health...
...pharmaceutical industry has been under criticism [by those who compare] what we produce versus what we charge...some of which is true," Scolnick said. "I don't think the industry has to apologize for anything. It should be very proud of its contributions to medicine...