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...Se-Jin Lee and his colleagues at the Johns Hopkins School of Medicine didn't set out to create muscle-bound lab specimens. As reported in last week's Nature, they wanted to find out how a particular protein, a growth factor called myostatin, regulates the development of tissue. So they produced a strain of mice in which the gene that codes for myostatin had been deleted, or "knocked out." The resulting mutant animals grew up normal in every way--except for their extraordinarily well-developed musculature...

Author: /time Magazine | Title: MIGHTY MOUSE | 5/12/1997 | See Source »

Even if it's part time. This year, Se-jin roamed the country for medical school interviews. Meanwhile, he played teaching fellow in Biochem 10, the introductory Biochemistry course, while spending every spare moment in the lab. "I did absolutely zero work in other courses," he laughs. But he did enough to get accepted at Johns Hopkins Medical school where he will pursue both an MD and a Ph.D. His research will continue on viruses, this time animal tumor viruses, under the direction of Dr. Dan Nathans, 1976 Nobel Laureate. That's seven more years of school, including summers...

Author: By Michael Stein, | Title: When It Works, It Really Works | 6/4/1981 | See Source »

...medical school when he wants to work in a lab? "I think medical school has more to offer than just teaching you to practice medicine. My education there will contribute to the type of researcher I am," he comments. As part of his MD-Ph.D program at Hopkins, Se-jin will be exempt from tuition in addition to receiving a $5,000 stipend each year...

Author: By Michael Stein, | Title: When It Works, It Really Works | 6/4/1981 | See Source »

...Unable to Regulate their P2 Helpers." He studied the relationship between two types of viruses where one helps the other to survive when they attack the same cell. How one helps the other, which genes are necessary for functions, and these are controlled: those are the compelling problems. And Se-jin waxes eloquent when listing his experiments and results--like a child sharing newly-learned multiplication tables...

Author: By Michael Stein, | Title: When It Works, It Really Works | 6/4/1981 | See Source »

...with critics and writers who know so much more than they do. In experimental science where the professor does no work at the bench, the actual contributions are made by his students. The work I do is in no way inferior to that of a graduate student or Ph.D.," Se-jin says. "It may take me longer and I may not see the interesting results as quickly," he says modestly, "but my work is just as worthwhile...

Author: By Michael Stein, | Title: When It Works, It Really Works | 6/4/1981 | See Source »

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