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Reporting this week in the Archives of General Psychiatry, scientists describe for the first time a set of genes, about 100 in all, that seem to predict how well a smoker will respond to two different types of quitting programs - nicotine replacement or bupropion (Zyban). Nicotine-replacement methods, including the patch, pill and gum, work by weaning the smoker off nicotine gradually, usually over a period of weeks or months. Bupropion, on the other hand, is an antidepressant, which does not contain nicotine; instead, it works to curb nicotine cravings by interfering with the reward circuit in the brain, where...

Author: /time Magazine | Title: A Genetic Clue to Quitting Smoking | 6/2/2008 | See Source »

...borrow up to $5,000 to start a new business if he can convince the Agency’s directors that it would be profitable and proper to set him up selling typewriters or toe-nail clippers. Within the rather vague limits of propriety, the opportunities for future hucksters seem boundless...

Author: By The Crimson Staff | Title: ...Who Help Themselves | 6/1/2008 | See Source »

Where demand cannot support two firms, in birthday cake sales, for example, the problem is more difficult. The best expedient would seem to be allowing all prospective cakemen to compete for the franchise each year, forcing the incumbent to show that he was providing quality and service at a fair price. If not, bureaucratic stagnation could easily set in, and overshadow the fine effects that the creation of Harvard Student Agencies, Inc., should have on the student employment field here...

Author: By The Crimson Staff | Title: ...Who Help Themselves | 6/1/2008 | See Source »

...wholly accurate to say Mitt Romney is unlikely to get that call from Sedona. There is no love between McCain and Romney; the two men don't care for each other, come from different wings of their party and have said some things that make Bush's "voodoo" remark seem harmless...

Author: /time Magazine | Title: The Week in Politics | 6/1/2008 | See Source »

...Past centuries may have seen catastrophic natural disasters, but the worst in the nation's recent history was a series of avalanches in the 1990s that killed over 30 people. But if the hundreds of volunteers, the dozens of converted emergency 4x4s, the strategic maps and the shelter tents seem like overkill in response to the day's minor toll, they also reflect the fragility and communal sense of responsibility fostered by Iceland's isolation. Since the U.S. military pulled out in 2006, Icelanders take the manifestations of their isolation - whether it's a lack of fresh produce or facing...

Author: /time Magazine | Title: The Loneliest Quake on the Planet | 6/1/2008 | See Source »

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