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...HEART--AND BEYOND. One drawback with all these techniques is that it takes time, usually several weeks, to grow organs using the patient's own cells. Although using these cells sidesteps the rejection problem, time is a luxury many patients, particularly heart patients, can't afford. So Michael Sefton, who directs the tissue-engineering center at the University of Toronto, has proposed building a "heart in a box"--complete with chambers, valves and heart muscles--from cells genetically engineered to block the signal with which the body marshals cells to attack invaders. Sefton envisions spin-offs along the way--like...

Author: /time Magazine | Title: How to Build a Body Part | 3/1/1999 | See Source »

...character than the snapshots suggest. She is so modest she neglected to tell her classmates at a high school reunion what she does for a living. "You almost had to drag it out of her that she worked at the White House," says Waukegan Township High School classmate Chandra Sefton. She is so reserved that she often uses only facial expressions to reveal her opinions. She keeps her private life so private that some of her co-workers were not really aware of her divorce, her courtship with the man who became her second husband, or the deaths last year...

Author: /time Magazine | Title: The Currie Riddle | 4/27/1998 | See Source »

...After that hard, dispiriting race she swore to her husband that she'd never work on another one. That vow lasted until the next one, when she got a call to come work for strategist James Carville at Clinton headquarters in Little Rock, Ark. Currie told high school friend Sefton that she was working for this guy Clinton because after years of backing losers, she thought he really had a chance. Before the race was over, she was working in the Governor's mansion...

Author: /time Magazine | Title: The Currie Riddle | 4/27/1998 | See Source »

...fury had apparently subsided. "For some reason I stayed up on deck," he recalled later. "The boat was sailing along really well and fast, and it was a nice feeling to be up there." That decision probably saved his life. "Those below did not stand a chance," said Philip Sefton, 22, also from Britain, who was at the helm. He described the deathly blow that struck the Marques 80 miles north of Bermuda: "It was totally unexpected. It was incredible in its velocity. It was a freak hurricane. The ship was on its side in less than ten seconds...

Author: /time Magazine | Title: It Meant to Kill Us | 6/18/1984 | See Source »

Everyone on deck was catapulted into the dark, heaving sea. "As she went under I levered myself onto the rail and was swept clear as she went under me," Sefton remembers. "As I stood on the poop rail I thought, 'Jump!' I went under water for a few seconds. A life raft was 30 ft. away. I thought, 'Oh God, swim!' " The orange rafts were designed to eject and inflate automatically in an emergency, and they did. Clifton McMillan, 16, of Fairfield, Conn., who had just finished his watch when the squall hit, managed to jump...

Author: /time Magazine | Title: It Meant to Kill Us | 6/18/1984 | See Source »

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