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Researchers discovered the first antidepressants purely by chance in the 1950s. Seeking a treatment for schizophrenia, scientists at the Munsterlingen asylum in Switzerland found that a drug that tweaked the balance of the brain's neurotransmitters - the chemicals that control mood, pain and other sensations - sent patients into bouts of euphoria. For schizophrenics, of course, that only made their condition worse. But researchers soon realized it made their pill perfect for patients with depression. On first trying it in 1955, some patients found themselves newly sociable and energetic and called the drug a "miracle cure." The drug, called imipramine...

Author: /time Magazine | Title: Antidepressants | 1/7/2010 | See Source »

...challenging their detention that they had brought in district court in Washington. Earlier last year, a Yemeni won his case and was repatriated and released. The Defense Department said it was comfortable releasing the six, as were the other departments, so in the end, Obama's national-security team sent them home. It is unclear whether they remain incarcerated in Yemen. (See pictures of the last days of Gitmo...

Author: /time Magazine | Title: Obama's Dilemma: What to Do with Yemenis in Gitmo | 1/7/2010 | See Source »

...Abdulmutallab, the Nigerian who allegedly tried to blow up a flight to Detroit on Christmas Day, trained for his mission with al-Qaeda operatives in Yemen has renewed attention on the nation as a breeding ground for extremists. Saleh - a professed U.S. Ally - has promised action and indeed has sent hundreds of extra soldiers to the front lines of al-Qaeda-dominated territory east of Sana'a. But U.S. officials view him as a fickle leader facing a difficult array of threats - from a sectarian rebellion in the north and a secessionist movement in the south, to say nothing...

Author: /time Magazine | Title: Yemen: The Most Fragile Ally | 1/7/2010 | See Source »

...senior Jordanian intelligence source tells TIME that al-Balawi was sent to Pakistan at the behest of the CIA, with a plausible cover story: he was to be a medical student pursuing advanced university studies. An official in Amman, who like his colleagues requested anonymity, says that once al-Balawi set himself up in Pakistan's border region and sent out feelers to jihadi militants, "he was very helpful, and the CIA were grateful to him." This source tells TIME that al-Balawi pinpointed several al-Qaeda targets, which were attacked by U.S. forces in Afghanistan, and that "al-Balawi...

Author: /time Magazine | Title: CIA Bomber Was No Double Agent, Say Jordanians | 1/7/2010 | See Source »

...Abdulmutallab case is that they are forced to sort through a massive tide of intelligence on a daily basis, two experts tell TIME. They note that the warnings about Abdulmutallab came from varying sources - including CIA intercepts in Yemen and the U.S. embassy in Nigeria - and were sent to different U.S. security organizations. Connecting the dots becomes more difficult when multiple streams of intelligence empty into several different lakes, the experts say. (See pictures of Umar Farouk Abdulmutallab...

Author: /time Magazine | Title: Flight 253: Too Much Intelligence to Blame? | 1/7/2010 | See Source »

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