Word: seriousnesses
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Earlier human trials have shown, however, that rapamycin can have serious side effects. Because it is an immunosuppressant, it can make users susceptible to opportunistic infections. It has also been linked to hyperlipidemia, or high levels of triglycerides in the blood, which can lead to heart disease. It's unclear whether these problems would counteract any longevity benefit that rapamycin might provide in humans. Says Strong, "I think more immediately, people are starting to look at [rapamycin] for age-related diseases like Alzheimer's disease, Parkinson's disease or kidney disease." The drug has also recently entered clinical trials...
California's crazy budget laws make it an extreme case, but that doesn't mean it's alone in financial duress - there are plenty of other states in serious hot water. (See how Americans are spending...
...study, Lyubomirsky found that people who did the same acts of kindness day after day for 10 weeks actually got less happy. But those who systematically varied their good deeds, got a boost. And, logically enough, effort counted. Letters of gratitude that reflected serious effort brought more satisfaction than those that seemed written routinely or out of duty. On the other hand, Lyubomirsky has also found that people who are clinically depressed "got less happy writing gratitude letters," perhaps because the effort was too much...
Their work is serious, even dangerous. As I venture from island to island on one of the motor yachts which are the preferred method of exploration (with the province’s government providing itineraries and carefully monitoring tourists), Fausto, our confident, loquacious guide tells us stories of local fishermen kidnapping CDF staff. The inhabitants of the Galapagos, a few thousand, relay on tourism and fishing for their welfare. The paradox here: The presence of these “indigenous” people jeopardizes the pristine ecosystems on which tourism—and therefore the inhabitants themselves—depends...
...Defense Secretary Robert] Gates spoke of your "fresh eyes." What have they shown you? The first thing I was struck by when I got here was that the security situation is very serious. I am not saying catastrophic, but it is very serious, and it warrants a very serious effort. So that didn't shock me, but it reinforced things that I had been seeing. The other observation is that there has been a tremendous number of people here doing a lot of good work - and that means the ANSF, parts of the Afghanistan government, UNAMA [United Nations Assistance Mission...