Word: serum
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Dates: during 1940-1949
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...stable preparation of serum albumin (TIME, Jan. 31), which is especially useful in shock. It is five times as powerful as plasma in drawing blood fluid back from the tissues into the blood stream. (Leakage of blood fluid into the tissues, with consequent reduction of blood volume and lowered blood pressure, are characteristics of shock...
...Seventeen young women suffered from severe acne associated with menstrual disorders. After injections of pregnant-mare serum (a blood extract rich in pituitary hormone), all but three of them developed clear skins, normal menses. Doctors are leary of sex-hormone treatment for acne-it has been "disappointing" in the past -but Drs. Charles Howard Birnberg and Charles Robert Rein of New York City believe that pregnant mare's serum is effective for this type of acne in women. They make no mention of men with acne...
...sulfapyridine. The sulfas almost seemed to be the dream drugs he had looked for. They stopped deadly streptococci, even cured pneumonia. But the more sulfa drugs were used, the clearer it became that they 1) sometimes delayed healing by irritating wound walls, 2) did not work well in serum or pus. When used internally, they can cause severe, sometimes fatal, toxic reactions (TIME...
...patient's spinal fluid. If the level is low, the infection is severe. Treatment begins with an injection of sulfadiazine and a continuous slow drip of salt solution into a vein. After the drip has gone on for about four hours, a measured amount of the special rabbit serum is put into the reservoir of weak salt solution. The amount used depends on the amount of infection. All the serum is given in two hours...
Next day the spinal fluid is tested again. If sugar and chlorides have come up to normal (they usually do in that time), the serum dose need not be repeated. After that, blood tests and sulfadiazine by mouth go on for a week, just in case...