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...Asparaginase. The story of L-asparaginase traces back to a 1953 observation by Cornell University's Dr. John G. Kidd that serum from normal, healthy guinea pigs killed some-but by no means all-types of cancer in mice, without harming the animals' other tissues. It took Cornell's Dr. John...

Author: /time Magazine | Title: Cancer: Secret from the Guinea Pigs | 4/14/1967 | See Source »

Allergic Reaction. Probably the first human being to receive the enzyme was a boy in Chicago who was dying of leukemia. After infusions of partially purified enzyme from guniea-pig serum, his white-cell count decreased, and so did the swelling of some of his organs. But his red-blood cells were being destroyed as an apparent side effect and treatment had to be stopped. The boy died of his leukemia. The problem of purification remains. Even the presumably safer material extracted from bacteria, in its currently purest form, causes allergic reactions in mice-as it did to some extent...

Author: /time Magazine | Title: Cancer: Secret from the Guinea Pigs | 4/14/1967 | See Source »

...memory was for the prosecution, it clouded under defense crossexamination. Shaw's lawyers established that Russo had once been under psychiatric care for 18 months, that he had been hypnotized three times by the prosecution physician and that he had been injected with sodium pentothal, the "truth serum," to help him "remember" details. With the defense hammering away, he was unable to recall exactly when or where he met Ferrie, how and when he had arrived at Ferrie's apartment the night he heard of the "plot," how he had traveled home afterward. Shaw's law yers...

Author: /time Magazine | Title: Investigations: The D.A. Wins a Round | 3/24/1967 | See Source »

...introduce antibody against the lymphocytes themselves. So thymus glands, spleens and lymph nodes are removed from human cadavers, and the extract is injected into horses. The horses' rejection mechanism goes to work and makes particles active against the human lymphocytes. The horses are later bled, antilymphocyte serum is extracted, and may be further refined to a globulin fraction. At the University of Colorado, a team headed by Dr. Thomas Starzl has performed 19 successful transplants since last June; given antilymphocyte globulin, the patients have got along well on sharply reduced doses of azathioprine and prednisone...

Author: /time Magazine | Title: Surgery: Circumventing Immunity | 3/10/1967 | See Source »

...help of her hirelings, a butler (Peter Jaszi) and a murderous Stillman nurse (Erica Ivers). The pair arranges the deaths of the roommate and girl friends, deaths which are duly certified by Stillman doctors and reported in the CRIMSON. In fact, however, through the agency of a potent serum they do not die at all but are transformed into zombies in the Francis Ave. house. I shall reveal no more of the plot which is fun and has its share of suspense...

Author: By Timothy S. Mayer, | Title: Sinister Madonna | 3/3/1967 | See Source »

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