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Fifteen years since the last discovery of its kind, scientists have finally identified a new set of genes that may contribute to Alzheimer's disease...
...current studies, researchers amassed the largest set of genetic data to date in the study of Alzheimer's, and took advantage of the most recent advances in genetic screening to determine which new genes conferred a high risk of developing the disease. "I think this technique is going to be very valuable, especially for diseases of the brain, where it is very difficult to get in there and see what's going on," says Julie Williams, professor of neuropsychological genetics at the MRC Center of Cardiff University, and one of the authors of the U.K. study, published today...
...conclusions the same way, comparing the genetic activity of their thousands of samples. Williams's team found that among the Alzheimer's patients' samples, certain versions of the genes that coded for clusterin and PICALM were more likely to be active, compared with the controls; in Amouyel's data set, clusterin and CR1 were the two highest ranking genes. While Amouyel's study had also noted PICALM as a high-risk gene of interest and Williams's research had likewise identified CR1, the two groups used different criteria to pinpoint their highest priority genes, leading to the slightly different rankings...
...scheme introduced in January to help would-be bosses bypass the formidable process of founding a small business. The scheme cuts through the jungle of administrative red tape usually required to launch a company, and dramatically lightens the heavy taxes and social charges companies pay. While other firms face set charges whether business is booming or bust, auto-entrepreneurs are taxed only on sales. (See pictures of the global financial crisis...
...Army's new mental-toughness initiative, set to kick off in October, is to be successful, it needs buy-in from the people it plans to train. It can be a tough sell. At Marine Corps Base Camp Lejeune, in N.C., Adam Credle, who teaches military, law enforcement and Coast Guard personnel how to drive boats equipped with machine guns really fast, has encouraged his students to try out the meditative techniques. So far, he's been rebuffed, though he continues to try to persuade them to give the discipline's central exercise a chance. The mental focusing technique...