Word: shapely
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...Western Ontario is supposed to be a really good team,” Broadbent said. “And we beat them really badly. This just shows that we’re in great shape right now. Everyone is playing so well...
Playing at No. 2, intercollegiate No. 2 Broadbent came away with an easy three game victory. As he continues to fight his way back from a sore knee that hampered him during the fall, Broadbent is working himself into shape with every match...
...lower TNK levels. Xencor's approach derives from a process Dahiyat invented in 1997 while a graduate student at Caltech. Instead of using time-consuming methods like trial and error, he asked a computer to figure out what mix of amino acids would make a protein of a particular shape. (Shape is important because a protein's structure determines its function. Just like a flathead screwdriver is appropriate for some jobs and a Philips for others, proteins' different shapes help them effectively attack different disease cells.) The desired shape is easy to figure out; finding the single protein...
...Dahiyat wanted to show that he could make a V-shaped protein with a coil falling off the top of one arm. His Caltech colleagues laughed, but off he went to the supercomputer at Caltech's famed Jet Propulsion Laboratory. "I said, here's the shape I want to make, tell us the sequence,'' he recalls. By the end of the day, the computer gave him billions of possible amino acid combinations and recommended the best one. Dahiyat threw that sequence into a small, tunnel-like device called an NMR spectrometer. About a minute later, Dahiyat noticed that...
...blatantly favoring certain politicians (such as hapless 1995 presidential candidate Edouard Balladur). In June Le Monde agreed not to proceed with libel lawsuits against the authors, who in turn agreed not to republish their book, but the damage was done. The paper's finances may be in worse shape than its reputation. It is carrying debt of at least €110 million, has had losses over the last three years of some €50 million, and has seen circulation drop by 4.66% in the last year. Colombani's partisans say that Plenel's editorial leadership is largely to blame; Plenel...