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Part of what makes the decision so complex is that even when the chromosomes present a clear message on gender, anatomy may contradict it. Consider Sherri, a 45-year-old tax attorney from San Diego. Although her sex chromosomes are unambiguously XY, there is no doubt that she is a woman. Sherri has androgen-insensitivity syndrome (AIS), a condition that affects prenatal development. All embryos start out with the rudiments of male and female reproductive systems. A sort of developmental tug-of-war ensues until, generally speaking, the male reproductive system predominates in XY fetuses and the female...

Author: /time Magazine | Title: Between The Sexes | 3/1/2004 | See Source »

...that prenatal testosterone. Because the genitalia cannot be masculinized, they assume a more female structure. But that's not all. In the complete form of AIS, the body cannot respond to testosterone at all and the baby develops as a female, although without a functioning reproductive system. When Sherri was 11, she was told that she could never bear children because she had been born with "twisted ovaries" that had to be removed when she was a baby. In fact, the "ovaries" were her testes. "No one ever explained to me what my medical condition was," Sherri says...

Author: /time Magazine | Title: Between The Sexes | 3/1/2004 | See Source »

Elijah, Julanne and Sherri all would have found life easier if less embarrassment and secrecy were associated with their condition. That's a goal the Intersex Society is working toward. Meanwhile, scientists hope that more sophisticated testing will eventually help doctors and families make more informed choices about how to treat intersexuals. New research on the genetics of sexual development shows, for example, that several of the genes that influence sex are not even located on the X or Y chromosomes. What it all boils down to, says Dr. Eric Vilain, a professor of human genetics, pediatrics and urology...

Author: /time Magazine | Title: Between The Sexes | 3/1/2004 | See Source »

...silk pajamas and writes a weekly column for Dawn in which he tracks corruption to the highest places, vows to stay put, as does sociologist and city planner Arif Hassan who campaigns to save the few remaining buildings from Karachi's regal colonial past. Roland De Souza, whose organization SHERRI fights against illegal land developers whom he says are often in cahoots with city nabobs and some military officers, also insists he will always call Karachi his home. They, along with many other die-hard citizens, find that Karachi possesses a dynamism missing in other Pakistani cities. It's what...

Author: /time Magazine | Title: To Have & Have Not | 6/9/2003 | See Source »

Frantic parents streamed back from work to pick up their children from area schools. As protective police helicopters hovered, residents shut themselves inside. Says Sherri Long, whose daughter Staci is a Tasker student: "People who needed to get prescriptions waited. We've got tapes due back at Blockbuster, and we'll just pay the fines...

Author: /time Magazine | Title: Inside The Sniper Manhunt | 10/21/2002 | See Source »

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