Word: shots
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...shot of 2009 H1N1 vaccine, instead of two, may generate a sufficient antibody response against the virus in children ages six months to nine years, researchers report...
Under current government recommendations, young children receive two doses of the vaccine, while adults get only one. The two-shot regimen for youngsters is based on a similar recommendation in this population for seasonal flu vaccination. Because their immune systems are still developing, and because they are less likely to harbor existing antibodies from previous bouts with the flu, children are less able to generate protective antibodies against the influenza virus than adults, requiring two doses of the shot. (See what you need to know about the H1N1 vaccine...
...latest study of an Australian H1N1 vaccine, a shot that is also distributed in the U.S., shows that a single dose containing the same amount of viral protein as two doses combined, can produce enough flu-fighting antibodies in nearly 93% of youngsters immunized. "The single-dose response is substantially better than responses to seasonal flu vaccines of past years," says Terry Nolan of the University of Melbourne, the lead author of the study. That's good news for parents and public health officials, particularly in light of the fact that about half of U.S. children never get their second...
...doses of vaccine, each containing 15 micrograms (mcg) of the virus antigen. The other half received two doses containing 30 mcg of the antigen each. In both cases, the second dose was given 21 days after the first. The researchers found that 21 days after receiving only one shot, 92.5% of children in the 15-mcg-dose group and 98% of those receiving the higher dose had generated sufficient antibodies against H1N1...
...results suggest that one shot of the lower-dose vaccine may generate just as many flu antibodies as the two shots U.S. children currently receive, each containing 7.5 mcg of viral antigen. The findings could factor into discussions that health officials have as they make up recommendations for next year's flu season. Having children get immunized only once, rather than twice, may help increase the percentage of kids who are protected against influenza...